When installing the System Center Virtual Machine Manager 2007 Self Service Portal on a 64-bit version of Microsoft Windows, you may encounter a Fatal Error if IIS is configured to run in 32-bit mode. This issue occurs when installing the SCVMM
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Read the complete post at http://blogs.technet.com/askcore/archive/2008/06/29/installing-scvmm-portal-to-x64-windows-fatal-error-during-installation-id-205.aspx